Recommendation of ESPEN Guidelines on Parenteral Nutrition: Hepatology
- Liver Cirrhosis: Provides amino acids at 1.2–1.5 g/kg body weight
Indications
- For treatment of hepatic encephalopathy in patients with cirrhosis/hepatitis
- In hepatic coma
- Nutrition support in patients with liver diseases requiring parenteral nutrition who are intolerant of general-purpose amino acid solutions
Dose
- 1.2 to 1.6 ml/kg body weight/hour, administration through the peripheral vein
Drip Rate
- 28 to 38 drops/min for 70 kg body weight patients
Benefits of 42% BCAA Present in Celemin HEPA
- Facilitates ammonia detoxification
- Reduces the uptake of AAAs & Tryptophan in the brain
- Helps to improve cerebral perfusion
- Stimulates hepatic protein synthesis
- Improves postoperative quality of life in hepatectomized patients
Composition of Celemin HEPA 8% w/v in 500 ml
| Component | Amount |
|---|---|
| Amino Acid | 40 gm |
| Total Nitrogen | 6.4 gm |
| Osmolarity | 770 mOsm/L |
| Total Energy | 160 Kcal |
Additional Information
- Most of the amino acids originate from vegetable sources, making them better tolerated in patients with end-stage liver failure.
- Overcome protein depletion in hepatic insufficiency.
